We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
Most Useful Reviews
9
Reduced pain significantly
641 people found this helpful
This product has greatly alleviated my pain and stiffness associated with severe myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia. I didn't expect it to help much, but within 20 minutes of taking a large dose, I realised I was no longer limping or in pain. I'm now taking six pills a day and experiencing much less pain. This supplement has also resolved my chronic constipation. I advise anyone suffering from ME/CFS or fibromyalgia to give it a try, as it might help you too.
Read More
9
Eliminated headaches
2 people found this helpful
After experiencing headaches, fatigue, and body aches, I consulted an endocrinologist who prescribed magnesium. Taking two capsules daily has virtually eradicated my headaches. It has significantly enhanced my quality of life!
Read More
6
Stimulating effect
266 people found this helpful
A good form of magnesium that didn't cause any side effects. The tablets are large but easy to swallow. Magnesium, important for our body, comes in different forms. In this supplement, it is malate which has a stimulating effect, particularly beneficial with fatigue. It's advised not to take it before bed; I drink three at night. I recommend it!
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.
Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
Read More
4
Limited magnesium effectiveness in CFS
Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review.
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).
Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.
While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.
Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
Read More
User Reviews
USERS' SCORE
Good
Based on 15 Reviews
8.4
All Reviews
Positive Reviews
Negative Reviews
9
Reduced pain significantly
641 people found this helpful
This product has greatly alleviated my pain and stiffness associated with severe myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia. I didn't expect it to help much, but within 20 minutes of taking a large dose, I realised I was no longer limping or in pain. I'm now taking six pills a day and experiencing much less pain. This supplement has also resolved my chronic constipation. I advise anyone suffering from ME/CFS or fibromyalgia to give it a try, as it might help you too.
Read More
9
Eliminated headaches
2 people found this helpful
After experiencing headaches, fatigue, and body aches, I consulted an endocrinologist who prescribed magnesium. Taking two capsules daily has virtually eradicated my headaches. It has significantly enhanced my quality of life!
Read More
6
Stimulating effect
266 people found this helpful
A good form of magnesium that didn't cause any side effects. The tablets are large but easy to swallow. Magnesium, important for our body, comes in different forms. In this supplement, it is malate which has a stimulating effect, particularly beneficial with fatigue. It's advised not to take it before bed; I drink three at night. I recommend it!
Read More
9
Relieves fatigue
196 people found this helpful
This medication acts as an energy booster for me, effectively relieving fatigue and providing extra strength to my body.
Read More
9
Life-changing benefits
20 people found this helpful
If you take these, gradually increase to three pills daily for safety. I initially rated it two stars but changed it to five! After experiencing side effects from switching magnesium types, I noticed significant improvements with continued use. Months later, along with regular Epsom baths and magnesium spray, my life has transformed. Originally taken for fibromyalgia and bowel issues, I've seen remarkable reduction in chronic fatigue and brain fog after two decades. My menstrual cycles have finally normalised, and I no longer need pain relievers regularly. Give it a try but ease into it, as reactions may vary.
Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a complex and debilitating condition characterized by profound fatigue that doesn’t improve with rest and worsens with physical or mental activity. This crippling fatigue is often accompanied by a variety of symptoms, including sleep disturbances, cognitive difficulties, muscle pain, and joint pain. Unlike typical tiredness, the fatigue experienced in CFS is long-lasting, and it can significantly hinder everyday activities and overall quality of life.
The precise cause of CFS remains unknown, but it is believed to be influenced by a combination of genetic, environmental, immunological, and psychological factors. Diagnosis primarily relies on a careful assessment of symptoms, as there are no definitive laboratory tests available. Treatment options focus on symptom management and may include lifestyle changes, physical therapy, medication for pain management, and cognitive behavioral therapy. Given the complexity and variability of the condition, individuals with CFS should consult healthcare professionals who specialize in this area to develop personalized management strategies.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
While there is ongoing research into the potential benefits of magnesium for various health conditions, including Chronic Fatigue Syndrome (CFS), definitive conclusions remain elusive. Magnesium plays a critical role in energy production, muscle function, and overall metabolism, which suggests it may provide some support for those suffering from CFS. Some anecdotal evidence and small-scale studies suggest that magnesium supplementation could help alleviate certain symptoms associated with fatigue, particularly if a deficiency is present. However, further extensive clinical studies are needed to establish a clear link between magnesium supplementation and improvement in CFS symptoms.
It's important for individuals considering magnesium supplementation to consult with a healthcare professional. They can determine individual needs and whether magnesium may be beneficial based on personal health profiles and existing conditions. Additionally, magnesium should not be viewed as a standalone solution for Chronic Fatigue Syndrome; a comprehensive approach that includes lifestyle changes, a balanced diet, and other treatments may be necessary for managing symptoms effectively.
Based on user reviews, individuals taking magnesium malate for Chronic Fatigue Syndrome generally report experiencing results within a short timeframe, often almost immediately after ingestion. For instance, one user noted a reduction in fatigue right after taking the supplement for the first time, mentioning that it seemed to alleviate their symptoms almost immediately (Read Review). Many others also indicated noticeable improvements in energy levels and fatigue reduction shortly after starting their regimen, highlighting magnesium malate's rapid absorption and effectiveness as a vital supplement for combatting fatigue (Read Review).
However, while immediate effects are common, some users experienced more gradual improvements over a few days to weeks. Many report that consistent daily use, such as taking the supplement multiple times a day, can lead to sustained energy boosts and further reductions in both fatigue and associated symptoms like headaches (Read Review). Overall, it seems that while some may find quick relief, others may need a bit more time for optimal results, emphasizing the importance of regular intake.
Magnesium supplementation shows potential as a complementary treatment for Chronic Fatigue Syndrome (CFS), although the research is not yet conclusive. A systematic review of various therapies for CFS, including magnesium, revealed limited effectiveness, with only small, preliminary studies indicating positive outcomes. While some patients have reported improvements in well-being and energy levels following magnesium treatment, the small sample sizes and biases in existing studies complicate the validity of these results [1].
Several studies have shown that low magnesium levels may correlate with symptoms of fatigue, and some clinical trials have demonstrated improvement in energy and pain relief among patients treated with magnesium sulfate. For instance, a randomized trial indicated that CFS patients receiving magnesium sulfate experienced significant benefits compared to those on a placebo [5]. However, despite these promising anecdotes and some positive findings, the scientific community recognizes the need for more rigorous and larger-scale studies to establish magnesium's efficacy conclusively for CFS treatment [4]. Until then, while magnesium may offer some relief, it should not be viewed as a standalone solution for managing chronic fatigue syndrome.
Based on user reviews, many individuals report significant improvements in symptoms related to fatigue and headaches after taking magnesium malate. One user noted that their headaches have been virtually eradicated after starting on two capsules daily, which has greatly enhanced their quality of life (Read Review). Other users have echoed similar experiences, describing magnesium malate as an effective energy booster. Many claim that it provides extra strength and effectively relieves fatigue, thereby allowing them to engage more fully in daily activities and family life (Read Review).
Moreover, several users reported not only improvements in energy levels but also positive effects on mood and stress management (Read Review). For individuals dealing with chronic fatigue syndrome or low-level inflammation, magnesium malate appears to be a beneficial supplement, leading to noticeable enhancements in overall well-being (Read Review). While results can vary, the general consensus among users is that consistent use of magnesium malate leads to meaningful alleviation of symptoms associated with fatigue and discomfort.
Users report a range of experiences when combining magnesium malate with other supplements for dealing with Chronic Fatigue Syndrome (CFS). Many individuals highlight that magnesium malate seems to complement their overall supplement regimen effectively. For instance, one user emphasized that magnesium malate is a fundamental ally for anyone suffering from CFS and noted its excellent absorption and immediate effects on fatigue (Read Review). Additionally, others indicated that they take magnesium malate alongside other health recommendations, like integrative approaches that include stress management, leading to significant overall health improvements (Read Review).
Furthermore, users frequently mention that magnesium malate fits seamlessly into their daily routines with various timing strategies, such as taking it in the morning and evening or alongside other supplements. This flexible dosing has led to substantial reductions in fatigue and headaches, enhancing their quality of life (Read Review)(Read Review). Overall, the consensus among users is that magnesium malate, when combined with other therapeutic options, can yield positive outcomes in managing chronic fatigue and bolstering energy levels.
Users report varying dosages of magnesium, particularly magnesium malate, for alleviating symptoms associated with Chronic Fatigue Syndrome. Many suggest taking it two to three times daily; for instance, one user experienced significant relief from headaches and fatigue after taking magnesium malate two to three times a day (Read Review). Another user mentioned taking magnesium malate both in the morning and evening, leading to marked improvements in their overall wellbeing (Read Review).
In terms of specific amounts, a user highlighted that their chelated magnesium supplement contained 140mg per tablet, which they took once at noon and before bed, crediting the malic acid for its effectiveness in relieving fatigue (Read Review). Overall, many users emphasize the importance of magnesium malate due to its higher absorption rate and lower likelihood of digestive upset compared to other forms of magnesium, making it a preferred option for combatting fatigue issues related to Chronic Fatigue Syndrome (Read Review).
7.5
Quick fatigue relief
I purchased it to address my magnesium needs. The packaging was excellent and all the quality ingredients seem good. I anticipate its effectiveness, as it appears to alleviate my fatigue almost immediately upon taking it.
7.5
Great absorption effects
1 people found this helpful
This is one of the best magnesium products available, undoubtedly the finest magnesium malate. It offers excellent absorption and has immediate effects on muscle and digestive fatigue. For anyone suffering from chronic fatigue syndrome, it serves as a fundamental ally.
9
Reduced fatigue
14 people found this helpful
I have had a headache at least once a week, requiring me to take analgesics frequently. Since using magnesium malate two to three times daily, I have noticed a significant reduction in headaches and fatigue. Though I was initially reluctant to take it due to my depression, I've noticed less trembling and headaches, allowing me to engage more with my family.
9
Eliminated headaches
2 people found this helpful
After experiencing headaches, fatigue, and body aches, I consulted an endocrinologist who prescribed magnesium. Taking two capsules daily has virtually eradicated my headaches. It has significantly enhanced my quality of life!
7.5
Balanced disposition
2 people found this helpful
We use this product at home and have noticed improvements in mood and a reduction in stress, resulting in less fatigue and a more balanced state. Our doctor's advice to strengthen our wellbeing truly made a difference.
7.5
Reduced inflammation
4 people found this helpful
My health issues included low-level inflammation and restless leg syndrome. My integrative doctor advised magnesium malate. Taking it both morning and evening has led to significant improvements, making me more resistant to stress and reducing headaches!
7.5
Recommended for fatigue
3 people found this helpful
Magnesium chelated with malic acid has a high absorption rate. Each tablet contains 140mg of magnesium, which I take one each at noon and before bed. Malic acid effectively relieves fatigue, making it a good option for those affected.
7.5
Improved energy supply
1 people found this helpful
Magnesium malate stands out compared to magnesium carbonate and citrate; it's better tolerated and less likely to disturb the stomach. It offers a slower release, resulting in a consistent magnesium supply, which is essential for energy production in the mitochondria. For those battling fatigue, it assists energy levels significantly. It’s an excellent choice for boosting energy and health.
4
Limited magnesium effectiveness in CFS
Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review.
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).
Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.
While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.
Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
8
Magnesium potentially benefits CFS patients
Red blood cell magnesium and chronic fatigue syndrome.
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.
Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
References
Alraek T, Lee MS, Choi TY, Cao H, Liu J. Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review. BMC Complement Altern Med. 2011;11:87. doi:10.1186/1472-6882-11-87
Manuel y Keenoy B, Moorkens G, Vertommen J, Noe M, Nève J, et al. Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium. J Am Coll Nutr. 2000;19:374.
Takahashi H, Imai K, Katanuma A, Sugaya T, Hisano K, et al. [A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate]. Arerugi. 1992;41:1605.
Uchida A. [Therapy of chronic fatigue syndrome]. Nihon Rinsho. 1992;50:2679.
Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991;337:757.