Overview

SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.6
USERS' SCORE
Good
Based on 15 Reviews
8.4
Supplement Facts
Serving Size: 3 Tablets
Amount Per Serving
%DV
Calories
10
 
Total Carbohydrate
3 g
1%*
Magnesium (as magnesium malate trihydrate)
425 mg
101%
Sodium
10 mg
<1%
Magnesium Malate Trihydrate
3.75 g
Malic Acid (as magnesium malate trihydrate and malic acid)
2.5 g

Top Medical Research Studies

8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium sulfate shows potential benefits
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.

After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows limited benefit for fatigue
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.

Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.

Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.

However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More

Most Useful Reviews

9
Reduced pain significantly
641 people found this helpful
This product has greatly alleviated my pain and stiffness associated with severe myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia. I didn't expect it to help much, but within 20 minutes of taking a large dose, I realised I was no longer limping or in pain. I'm now taking six pills a day and experiencing much less pain. This supplement has also resolved my chronic constipation. I advise anyone suffering from ME/CFS or fibromyalgia to give it a try, as it might help you too.
Read More
9
Eliminated headaches
2 people found this helpful
After experiencing headaches, fatigue, and body aches, I consulted an endocrinologist who prescribed magnesium. Taking two capsules daily has virtually eradicated my headaches. It has significantly enhanced my quality of life!
Read More
6
Stimulating effect
266 people found this helpful
A good form of magnesium that didn't cause any side effects. The tablets are large but easy to swallow. Magnesium, important for our body, comes in different forms. In this supplement, it is malate which has a stimulating effect, particularly beneficial with fatigue. It's advised not to take it before bed; I drink three at night. I recommend it!
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.6
  • All Researches
8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium shows limited benefit for fatigue
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.

Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.

Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.

However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
7
Magnesium sulfate shows potential benefits
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.

After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows promise for CFS
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.

Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
Read More
4
Limited magnesium effectiveness in CFS
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).

Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.

While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.

Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
Read More

User Reviews

USERS' SCORE
Good
Based on 15 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Reduced pain significantly
641 people found this helpful
This product has greatly alleviated my pain and stiffness associated with severe myalgic encephalomyelitis/chronic fatigue syndrome and fibromyalgia. I didn't expect it to help much, but within 20 minutes of taking a large dose, I realised I was no longer limping or in pain. I'm now taking six pills a day and experiencing much less pain. This supplement has also resolved my chronic constipation. I advise anyone suffering from ME/CFS or fibromyalgia to give it a try, as it might help you too.
Read More
9
Eliminated headaches
2 people found this helpful
After experiencing headaches, fatigue, and body aches, I consulted an endocrinologist who prescribed magnesium. Taking two capsules daily has virtually eradicated my headaches. It has significantly enhanced my quality of life!
Read More
6
Stimulating effect
266 people found this helpful
A good form of magnesium that didn't cause any side effects. The tablets are large but easy to swallow. Magnesium, important for our body, comes in different forms. In this supplement, it is malate which has a stimulating effect, particularly beneficial with fatigue. It's advised not to take it before bed; I drink three at night. I recommend it!
Read More
9
Relieves fatigue
196 people found this helpful
This medication acts as an energy booster for me, effectively relieving fatigue and providing extra strength to my body.
Read More
9
Life-changing benefits
20 people found this helpful
If you take these, gradually increase to three pills daily for safety. I initially rated it two stars but changed it to five! After experiencing side effects from switching magnesium types, I noticed significant improvements with continued use. Months later, along with regular Epsom baths and magnesium spray, my life has transformed. Originally taken for fibromyalgia and bowel issues, I've seen remarkable reduction in chronic fatigue and brain fog after two decades. My menstrual cycles have finally normalised, and I no longer need pain relievers regularly. Give it a try but ease into it, as reactions may vary.
Read More

Frequently Asked Questions

7.5
Quick fatigue relief
I purchased it to address my magnesium needs. The packaging was excellent and all the quality ingredients seem good. I anticipate its effectiveness, as it appears to alleviate my fatigue almost immediately upon taking it.
7.5
Great absorption effects
1 people found this helpful
This is one of the best magnesium products available, undoubtedly the finest magnesium malate. It offers excellent absorption and has immediate effects on muscle and digestive fatigue. For anyone suffering from chronic fatigue syndrome, it serves as a fundamental ally.
9
Reduced fatigue
14 people found this helpful
I have had a headache at least once a week, requiring me to take analgesics frequently. Since using magnesium malate two to three times daily, I have noticed a significant reduction in headaches and fatigue. Though I was initially reluctant to take it due to my depression, I've noticed less trembling and headaches, allowing me to engage more with my family.
9
Eliminated headaches
2 people found this helpful
After experiencing headaches, fatigue, and body aches, I consulted an endocrinologist who prescribed magnesium. Taking two capsules daily has virtually eradicated my headaches. It has significantly enhanced my quality of life!
7.5
Balanced disposition
2 people found this helpful
We use this product at home and have noticed improvements in mood and a reduction in stress, resulting in less fatigue and a more balanced state. Our doctor's advice to strengthen our wellbeing truly made a difference.
7.5
Reduced inflammation
4 people found this helpful
My health issues included low-level inflammation and restless leg syndrome. My integrative doctor advised magnesium malate. Taking it both morning and evening has led to significant improvements, making me more resistant to stress and reducing headaches!
7.5
Recommended for fatigue
3 people found this helpful
Magnesium chelated with malic acid has a high absorption rate. Each tablet contains 140mg of magnesium, which I take one each at noon and before bed. Malic acid effectively relieves fatigue, making it a good option for those affected.
7.5
Improved energy supply
1 people found this helpful
Magnesium malate stands out compared to magnesium carbonate and citrate; it's better tolerated and less likely to disturb the stomach. It offers a slower release, resulting in a consistent magnesium supply, which is essential for energy production in the mitochondria. For those battling fatigue, it assists energy levels significantly. It’s an excellent choice for boosting energy and health.
4
Limited magnesium effectiveness in CFS
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).

Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.

While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.

Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
7
Magnesium shows promise for CFS
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.

Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.

References

  1. Alraek T, Lee MS, Choi TY, Cao H, Liu J. Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review. BMC Complement Altern Med. 2011;11:87. doi:10.1186/1472-6882-11-87
  2. Manuel y Keenoy B, Moorkens G, Vertommen J, Noe M, Nève J, et al. Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium. J Am Coll Nutr. 2000;19:374.
  3. Takahashi H, Imai K, Katanuma A, Sugaya T, Hisano K, et al. [A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate]. Arerugi. 1992;41:1605.
  4. Uchida A. [Therapy of chronic fatigue syndrome]. Nihon Rinsho. 1992;50:2679.
  5. Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991;337:757.
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